300 Colvin Woods Pkwy
Tonawanda, NY 14150, USA

Laboratory Design-Build Solutions

Danforth Cleanrooms and Laboratory Solutions provides Turnkey mechanical design, Laboratory equipment selection, Laboratory planning and layout and construction.  In addition, we provide for commissioning and comprehensive maintenance of your Laboratory facilities.

The Laboratory design process begins with identifying the specific needs of the space based upon its purpose.  Laboratory Managers, Facilities Managers and R&D Managers are just some of the positions often involved in the design process with our team.  These managers typically are responsible for planning, budgeting and monitoring construction projects related to their Laboratory facilities. Laboratories are environments that experience high Churn rates with processes and personnel.  This is due, in large part, to the constantly changing scope of the work being done in the lab, and is also related to the ever advancing state of technology.   Whatever your particular reason a scope of work must be established for the design process before any real work begins.

 Laboratory personnel will often work with staff from Facilities Engineering and Purchasing to prepare a written description of what work is required, the schedule of the work, and the budget allotted to the project. Danforth is uniquely qualified to work directly with you to assess your needs, prepare a scope of work and develop a cost proposal and schedule for your lab construction project.

Laboratory projects typically flow in this sequence:

Initial Charette to understand and qualify the needs of the space

  • People
  • Process
  • Equipment Requirements
  • Environmental requirements

Allocated Budget

Initially, we meet with your team to understand how you need to operate in your new Laboratory Environment.  We work to understand the constraints you may have with respect to space, budget and schedule so that we can build a plan of execution for your Laboratory project that exceeds your expectations and integrates seamlessly into your daily operations.


  • Conceptual Design
  • Single Line/ 2 Line drawings
  • Project cost estimates and Final Proposal
  • Buildable design drawings signoffs and approvals

Design-phase services include working with customers from schematic planning, to construction documents. The objective of this phase is to build a plan to execute the work within a time frame, a budget and in a manner conducive to working around existing operations at your facility. Danforth draws upon our design experience in the fields of HVAC, plumbing, lab equipment selection, and maintenance services to prepare specialized construction documents tailored to the needs of our customer.

Equipment and Subcontract Release Phase

  • Final equipment submittals review and release
  • Final subcontract documents and release

Once our Design is approved, we compile detailed equipment requirements and lay out the release dates for each component so that equipment arrives at appropriate times throughout the construction phase.  This is when we review each selection and confirm details such as power requirements, structural loads, fits and finishes to eliminate surprises during installation.  This is where we conduct our “Design Commissioning” to test each one of our design decisions.

Construction Phase

  • Shell construction
  • Laboratory Fume hoods, Casework and equipment installation
    Mechanical, Electrical and Plumbing installation
  • Envelope finishes including floors, walls, ceilings
  • Check, Test and Start of all equipment
  • Commissioning of Laboratory
  • Certification of Fume Hoods and Exhaust Points

During Construction we hold frequent team progress meetings and conduct our “Commissioning During Construction” and then “Final Commissioning” to ensure we stay on track with our design and our schedule and that the project functions as it was designed.  It is critical that each team member stay involved including our client, so that we can maintain consistency and open communication. 

Owner Training and Signoff on Laboratory Project

This is where you take charge of Your new Laboratory Environment!  We want to ensure that you are comfortable and familiar with your new environment and that you know how to maintain it.


Standards and Codes relevant to Laboratory Design

Some of the standards that govern laboratory and fume hood design and installation include: OSHA, EPA, NIOSH, and FDA.   Here is a summary of these agency standards:

OSHA Part 1910.1450. OSHA is the Occupational Safety and Health Administration. These regulations regarding fume hood operation are listed in the Code of Federal Regulations Volume 29 Part 1910.1450. This code handles some components of laboratory design and laboratory operation. It also touches upon airflow at the face of fume hoods, as well as the monitoring, maintenance and exhaust of chemical fume hoods.

ANSI/ASHRAE 110-1995. Method of Testing Performance of Laboratory Fume Hoods. This standard is generated by the American National Standards Institute and the American Society of Heating, Refrigerating and Air Conditioning Engineers. This standard primarily deals with methods of testing chemical fume hoods verify their operation.

ANSI/AIHA Z9.5. This is “The American National Standard for Laboratory Ventilation” and is published by ANSI and the American Industrial Hygiene Association. The standard covers a variety of lab ventilation issues including chemical fume hood monitoring, face velocities and exhaust.

NFPA 45. The National Fire Protection Association has developed a standard that makes recommendations for chemical fume hood construction, location, fire protection, specialty hoods, identification, inspection, testing and maintenance and exhaust.

SEFA 1.2-1996. The Scientific Equipment & Furniture Association published “Laboratory Fume Hoods Recommended Practices” which identifies design requirements for chemical fume hoods and covers issues such as sash face velocities and testing.

When you are ready to expand your existing laboratory or build a new one, Danforth is prepared to assist you from start to finish.  Contact us now to schedule an introductory meeting and see how our Cleanrooms and Laboratory Solutions group can Solve the Equation for you!   Toll Free: (800) 888-6119